文献类型：期刊文献

英文题名：Construction of 1H-pyrrol-2-ylphosphonates via [3+2] cycloaddition of phosphate azomethine ylides with ynones

作者：Meng, Jiang[1];Wu, Di[1];Shi, Ying[1];Yu, Xingxin[1];Deng, Wei-Ping[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2015

卷号：71

期号：7

起止页码：1074

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000349061600010)，CCR-EXPANDED(收录号:WOS:000349061600010)】；

基金：This research is sponsored by Shanghai Pujiang Program (14PJD013), Shanghai Yangfan Program (14YF1404600) and Fundamental Research Funds for the Central Universities (WY1414023).

语种：英文

外文关键词：[3+2] Cycloaddition; Pyrrole; Phosphonate azomethine ylide; Ynone; 1H-Pyrrol-2-ylphosphonate

摘要：An efficient route for the construction of 1H-pyrrol-2-ylphosphonates via the [3+2] cycloaddition of phosphonate azomethine ylides with ynones is described. This transformation proceeds with good functional group tolerance under mild conditions with good efficiency and selectivity. And the synthesis of 1H-pyrrol-2-ylphosphonates could also be achieved via the three-component reaction of benzaldehydes, aminomethyl phosphonates and ynones. (C) 2015 Elsevier Ltd. All rights reserved.