文献类型：期刊文献

英文题名：Palladium-catalyzed direct mono-α-arylation of α-fluoroketones with aryl halides or phenyl triflate

作者：Zhou, Jun[1,2];Fang, Xiang[1,2];Shao, Tongle[1,2];Yang, Xueyan[1,2];Wu, Fanhong[1,2,3]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Shanghai Inst Technol, Sch Chem & Environm Engn, 120 Caobao Rd, Shanghai 200235, Peoples R China

年份：2016

卷号：191

起止页码：54

外文期刊名：JOURNAL OF FLUORINE CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000388058300007)，CCR-EXPANDED(收录号:WOS:000388058300007)】；

基金：The authors thank the National Natural Science Foundation of China (No. 21672151) for financial support.

语种：英文

外文关键词：Palladium-catalyzed reaction; Mono-alpha-arylation; alpha-Aryl-alpha-fluoroketones

摘要：A palladium catalyzed Negishi-type alpha-arylation of alpha-fluoroketones with electron-rich and electron deficient aryl halides or phenyl triflate has been developed. This direct mono-alpha-arylation method generate a variety of ternary alpha-aryl-alpha-monofluoroketones easily in good to excellent yields using XPhos as ligand and Cs2CO3 as mild base. (C) 2016 Elsevier B.V. All rights reserved.