文献类型：期刊文献

中文题名：一年和二年生人工种植唐古特大黄蒽醌类成分的变化

英文题名：Change of anthraquinones in 1-2-year-old cultivated Rheum tanguticum

作者：周利[1];陈桂琛[2];史萍[1]

机构：[1]华东理工大学生物反应器工程国家重点实验室,上海200237;[2]中国科学院西北高原生物研究所,青海西宁810001

年份：2011

卷号：33

期号：2

起止页码：297

中文期刊名：中成药

外文期刊名：Chinese Traditional Patent Medicine

收录：CSTPCD;;北大核心:【北大核心2008】；CSCD:【CSCD2011_2012】；

基金：中科院西北高原生物研究所客座研究人员基金(F200-9-28);上海市浦江人才计划(10PJ1402300)

语种：中文

中文关键词：人工栽培唐古特大黄;蒽醌;高效液相色谱

外文关键词：cultivated Rheum tanguticum; anthraquinones; HPLC

摘要：目的:测定和比较一年期和二年期生长的人工种植唐古特大黄中游离和结合型蒽醌类成分的变化。方法:利用HPLC和UV法测定大黄中芦荟大黄素、大黄酸、大黄素、大黄酚和大黄素甲醚和总蒽醌含量,并与市售成品进行比较。结果:研究显示,生长期从一年增加到二年间,蒽醌类成分随着时间的增加有所增加;大黑沟种植的一年期大黄中游离大黄素甲醚含量已接近市售成品大黄的含量;大黑沟和群加种植的一年期大黄中结合大黄酸的含量均高于市售成品大黄的含量。结论:研究结果可为一年期人工种植唐吉特大黄资源开发,可望取代野生唐吉特大黄提供依据。
AIM：To assay and compare contents of anthraquinones between annual and biennial cultivated Rheum tanguticum from Qinghai Province.METHODS： The free five anthraquinone contents,including aloe-emo-din,rhein,emodin,chrysophanol and physcion,and the total anthraquinone contents in cultivated Rheum tangutic-um and pheum tinguticum on the market were analyzed using C18 RP-HPLC and UV spectrophotometer,respective-ly.RESULTS： The results showed that the contents of either five free anthraquinones or the combined ones were increased with the increase in the growth period.The physcion content in annual cultivated Rheum tanguticumgrowing in Daheigou was close to the one on the market,and the rhein content in annual cultivated Rheum tangutic-um growing both in Daheigou and Qunjia was more than the one on the market.CONCLUSION：Providing datafor the use of annual cultivated Rheum tanguticum to replace the wild one.