文献类型：期刊文献

中文题名：线性-树枝状两亲聚合物及其胶束的制备和聚集行为

英文题名：Preparation and Aggregation Behavior of Linear-Dendritic Amphiphilic Polymer and Micelles

作者：惠志倩[1];郭睿[2];龚飞荣[3];戎宗明[1]

机构：[1]华东理工大学化学与分子工程学院,上海200237;[2]巴斯夫上海涂料有限公司,上海201108;[3]华东理工大学材料科学与工程学院,上海200237

年份：2016

卷号：42

期号：6

起止页码：800

中文期刊名：华东理工大学学报（自然科学版）

外文期刊名：Journal of East China University of Science and Technology

收录：CSTPCD;;Scopus;北大核心:【北大核心2014】；CSCD:【CSCD2015_2016】；

语种：中文

中文关键词：聚乙二醇单甲醚;聚乳酸;线性-树枝状聚合物;自组装;胶束

外文关键词：methoxy poly （ ethylene glycol ） ; poly （L-lactide） ; liner-dendritic polymer; self-assembly; micelles

摘要：以聚乙二醇单甲醚（mPEG）为原料,制备大分子引发剂mPEG-Gn-OH2n（n=1,2,3,4）,以异辛酸亚锡为催化剂,引发L-丙交酯开环聚合,通过控制丙交酯和大分子引发剂的投料比,合成1~4代线性-树枝状两亲聚合物。基于聚合物自组装特性,通过透析法制备聚合物胶束,采用核磁氢谱、渗透凝胶色谱对聚合物结构进行表征,使用动态激光光散射技术、电子扫描显微镜和透射电镜对其聚集体进行观测。研究表明,胶束流体力学直径主要受代数影响,并随PEG链段增加而增大,胶束粒径为200~300nm。胶束形状反映聚合物分子中亲水、亲油比,当聚合物分子中亲水链段EO体积分数φEO〈0.35时,线性-树枝状两亲聚合物才能形成空心胶束。
The mPEG-Gn-OH2n （n= 1,2,3,4） was prepared as a macroinitiator through iterative process with the methoxy poly （ethylene glycol） as reactant and then they were used in the ring-opening polymerization of L-lactide （LA） with the catalyst stannous octoate （Sn（Oct）2） . By controlling the feed ratio of LA and macroinitiator, one to four generations of linear-dendritic amphiphilic polymers could be obtained. Then,polymer micelles were self-assembled by dialysis method. The structure of polymers were characterized by ^1H-NMR and GPC, and the aggregations were observed by DLS, SEM and TEM. The results show that the hydrodynamic diameter of micelles are highly influenced by the generations and increased gradually with the increase of the poly （ethylene oxide） （PEO） chains. The size of micelles is verified about 200 to 300 nm. Generally, the shape of micelles is a feature of the hydrophilic-hydrophobic ratio,and the hollow spherical micelles will be formed only when the volume fraction of EO block （φEO） is less than 0.35.