文献类型：期刊文献

英文题名：C-H Borylation of Diphenylamines through Adamantane-1-carbonyl Auxiliary by BBr3

作者：Wu, Gaorong[1,2];Fu, Xiaopan[1,2];Wang, Yangyang[1,2];Deng, Kezuan[1,2];Zhang, Lili[1,2];Ma, Tao[3];Ji, Yafei[1,2]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[3]Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 102488, Peoples R China

年份：2020

卷号：22

期号：17

起止页码：7003

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000569377600060)】；

基金：We gratefully thank the National Natural Science Foundation of China (Project No. 21676088) for financial support.

语种：英文

摘要：A method for ortho-C-H borylation of diphenylamines using BBr3 as the boron source has been reported. The noncatalytic adamantane-1-carbonyl directed reaction exhibited site exclusivity and good functional group tolerance. Generally, the borylation occurred at the more electron-rich aromatic ring and the borylated products could be converted to various useful intermediates. Besides, the derived arylation and removal of auxiliary of the product could be achieved in a one-pot fashion.