文献类型：专利

英文题名：New N,N'-substituted aryl urea derivative used as multi-target kinase inhibitor for solid tumors and for developing anticancer medicine

作者：LI J;LIU Y;ZHU J;CHEN Y;DING P;HUANG H;WU D;LIU L

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN103288823-B

公开日：2015-02-18

语种：英文

收录：DERWENT

摘要：NOVELTY - An N,N'-substituted aryl urea derivative (I) or salt is new. USE - N,N'-substituted aryl urea derivative used as multi-target kinase inhibitor for solid tumors and for developing anticancer medicine (claimed). DETAILED DESCRIPTION - An N,N'-substituted aryl urea derivative (I) or salt is new. R1=piperidinone of formula (II) or (III); R2=6-membered hetero aromatic ring or substituted 6-membered aromatic ring; and R3=H, 1-6C alkyl substituted six-membered aromatic ring of 1-4 1-6C alkyl, 1-6C perfluoroalkyl or halo.