文献类型：期刊文献

英文题名：Structure-guided design of a covalent inhibitor targeting the methyltransferase MLL1 with anti-leukemic activity

作者：Zheng, Y.[1,2];Zhao, L.[3];Li, Y.[4,5];Feng, W.[4];Xu, Y.[4];Chen, Y.[3];Quan, S.[1,2]

机构：[1]Shanghai Jiao Tong Univ, State Key Lab Microbial Metab, Sch Life Sci & Biotechnol, Shanghai, Peoples R China;[2]Shanghai Jiao Tong Univ, Zhangjiang Inst Adv Study, Shanghai, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, Ctr Excellence Mol Cell Sci, State Key Lab Mol Biol,Key Lab Epigenet Regulat &, Shanghai, Peoples R China;[4]East China Univ Sci & Technol, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, Sch Biotechnol, Shanghai, Peoples R China;[5]Shanghai Jiao Tong Univ, Renji Hosp, Shanghai Canc Inst, State Key Lab Syst Med Canc,Sch Med, Shanghai, Peoples R China

年份：2026

卷号：16

起止页码：S274

外文期刊名：FEBS OPEN BIO

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001840847600467)】；

语种：英文