文献类型：期刊文献

英文题名：Flexible electrochemical sensor with Fe/Co bimetallic oxides for sensitive analysis of glucose in human tears

作者：Zhou, Fangfang[1];Zhao, Hongli[1];Chen, Kaicha[1];Cao, Shida[1];Shi, Zehui[1];Lan, Minbo[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Res Ctr Anal & Test, Shanghai 200237, Peoples R China

年份：2023

卷号：1243

外文期刊名：ANALYTICA CHIMICA ACTA

收录：;EI(收录号：20230413419046);WOS:【SCI-EXPANDED(收录号:WOS:000964174500001)】；

基金：This work was supported by the Science and Technology Commission of Shanghai Municipality (STCSM, 20520712500, 21JM0010400) ; and the Fundamental Research Funds for the Central Universities (JKJ01221718) .

语种：英文

外文关键词：Flexible electrode; Bimetallic oxides; Uniformly dispersed structure; Glucose detection; Human tears

摘要：The construction of uniformly dispersed structure with abundant active sites is crucial for fast electron transport and advancing electrocatalytic reactions. Herein, FexCoyO4-rGO was prepared by depositing Fe and Co bimetallic oxides in-situ on reduced graphene oxide through a simple process combined hydrothermal reaction and calcination. Fe was elaborately introduced into the synthesis of metal oxides to alleviate the aggregation of cobalt oxides and obtain nanocomposites with homogeneously structured and abundant redox sites, and the bimetallic oxides nanomaterials had enhanced electrocatalysis under the synergistic effect. The flexible electrode prepared from FexCoyO4-rGO exhibited excellent detection performance for glucose with a detection limit down low to 0.07 mu M and a sensitivity of 1510 mu M cm-2 mA-1. The adoption of flexible substrates improved the wearability of the electrode and broadened its practicality for detecting biomarkers on the skin surface. The constructed sensor was successfully used in the dynamic analysis of glucose content in tears, and the results were highly consistent with the test outcome of a commercial test kit, demonstrating its application prospects in non-invasive epidermal diabetes mellitus diagnosis.