文献类型：期刊文献

英文题名：Asymmetric [4+2] Annulations of Isatins with But-3-yn-2-one

作者：Wang, Qiang[1,2];Lian, Zhong[1,2];Xu, Qin[1,2];Shi, Min[1,2,3]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2013

卷号：355

期号：17

起止页码：3344

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000327984000003)，CCR-EXPANDED(收录号:WOS:000327984000003)】；

基金：We thank the Shanghai Municipal Committee of Science and Technology (11JC1402600), the National Basic Research Program of China (973)-2010CB833302, and the National Natural Science Foundation of China for financial support (21102166, 21072206, 20472096, 20872162, 20672127, 21121062 and 20732008).

语种：英文

外文关键词：asymmetric [4+2]annulations; but-3-yn-2-one; Cinchona alkaloids; isatins; spiro[indoline-3,2 '-pyran]s

摘要：The catalytic asymmetric [4+2]annulations of isatins with but-3-yn-2-one catalyzed by the Cinchona alkaloids-derived oragnocatalyst (DHQD)(2)PHAL have been developed in the presence of 3.0equivalents of D-diethyl tartrate in the mixed solvent (diphenyl ether/diethyl ether=1/1) or a slightly modified one, affording the corresponding substituted spiro[indoline-3,2-pyran]-2,4(3H)-diones in good to excellent yields with high enantioselectivities under mild conditions.