文献类型：期刊文献

英文题名：Immunosuppressive Withanollides from Withania coagulans

作者：Huang, Chao-Feng[2];Ma, Lei[1];Sun, Li-Juan[1];Ali, Mumtaz[3];Arfan, Mohammad[3];Liu, Jian-Wen[1];Hu, Li-Hong[1,2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China;[3]Univ Peshawar, Inst Chem Sci, Peshawar, Pakistan

年份：2009

卷号：6

期号：9

起止页码：1415

外文期刊名：CHEMISTRY & BIODIVERSITY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000270429900011)】；

语种：英文

摘要：Six new withanolides, withacoagulins A-F (1-6, resp.), together with ten known withanolides, 7-16, were isolated from the aerial parts of Withania coagulans. Their structures were determined by spectroscopic techniques including 1D- and 2D-NMR (H-1, C-13, HMQC, and HMBC) and MS experiments. These compounds, including the crude extracts of this herb, exhibited strong inhibitory activities on the T- and B-cell proliferation.