文献类型：期刊文献

英文题名：Triple-locked fluorescent probes sequentially activated by hNQO1, LAP and FA: application in bioimaging of cancer cells

作者：Zhou, Langping[1];Chen, Han[1];Zhang, Weibing[1];Qian, Junhong[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2025

卷号：61

期号：41

起止页码：7442

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20251718314254);WOS:【SCI-EXPANDED(收录号:WOS:001475056800001)】；

基金：This work was supported by National Key Research and Development Program of China (Grant: 2022YFD1700400).

语种：英文

外文关键词：Cancer cells - Cells

摘要：Two fluorescent probes, subsequently activated by hNQO1, LAP and FA, were rationally designed for simultaneous detection of the above three analytes. Both probes could bioimage cancer cells overexpressing hNQO1, LAP and FA. Biotin-bearing probe NP3-Bio could discriminate between cancer cells and hypoxic normal cells.