文献类型：期刊文献

英文题名：Design of C2-symmetric salen ligands and their Co(II)- or Yb(III)-complexes, and their role in the reversal of enantioselectivity in the asymmetric Henry reaction

作者：Wu, Shengying[1,2];Tang, Jun[1,2];Han, Jianwei[3];Mao, Dan[1,2];Liu, Xin[1,2];Gao, Xing[1,2];Yu, Jianjun[1,2];Wang, Limin[1,2]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai 200032, Peoples R China

年份：2014

卷号：70

期号：35

起止页码：5986

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000340336000077)】；

基金：This research was supported by the National Nature Science Foundation of China (NSFC, 21272069, 20672035), the Fundamental Research Funds for the Central Universities and Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

语种：英文

外文关键词：Co(II) complex; Yb(III) complex; Enantioselectivity reverse; Lewis acid/base bifunctional catalyst; Henry reaction

摘要：Reversal of enantioselectivity in asymmetric Henry reactions was achieved with novel chiral C-2-symmetric salen ligands bearing morpholine moieties by changing the Lewis acid center from Co(II) to Yb(III). The possible transition state models were supported by mass spectrometry experiments. (C) 2014 Elsevier Ltd. All rights reserved.