文献类型：期刊文献

英文题名：A well-defined unimolecular channel facilitates chloride transport

作者：Chen, Sujun[1];Zhao, Yongliang[1];Bao, Chunyan[1];Zhou, Yaowu[1];Wang, Chenxi[1];Lin, Qiuning[1];Zhu, Linyong[1]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2018

卷号：54

期号：10

起止页码：1249

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000423784500022)】；

基金：This work was supported by the NSFC (21472044 and 21425311) and The Program for Professor of Special Appointment (Eastern Scholar) at the Shanghai Institutions of Higher Learning.

语种：英文

摘要：A unimolecular ion channel was optimized by functionalization with a new type of rigid-rod oligomer. The macrocycle pendant endows chloride selectivity and the fluorescence feature and suitable length of the rod facilitates the visual insertion of channels into the lipid bilayer, resulting in efficient ion transport with an EC50 value of 0.36 mu M.