文献类型：期刊文献

中文题名：金复合介孔SBA-15吸附血红蛋白在H_2O_2电催化反应中的应用

英文题名：Adsorption of Hemoglobin on Au-modified Mesoporous SBA-15 and Application in Electrocatalysis of H_2O_2 Solution

作者：周丽绘[1];鲜跃仲[2];周宇艳[2];胡军[1];刘洪来[1]

机构：[1]华东理工大学化学系先进功能材料与制备教育部重点实验室,上海200237;[2]华东师范大学化学系,上海200062

年份：2005

卷号：63

期号：23

起止页码：2117

中文期刊名：化学学报

外文期刊名：Acta Chimica Sinica

收录：CSTPCD;;Scopus;北大核心:【北大核心2004】；CSCD:【CSCD2011_2012】；

基金：国家自然科学基金(Nos.20236010;20476025);上海市教委资助项目.

语种：中文

中文关键词：介孔SBA-15;金;血红蛋白;H2O2;电催化反应

外文关键词：mesoporous SBA-15; gold; Hb; H2O2; electrocatalysis

摘要：以P123嵌段共聚物表面活性剂为模板剂制备介孔氧化硅SBA-15,并用沉积-沉淀(DP)法在SBA-15介孔表面负载纳米Au颗粒制备得到金复合介孔SBA-15材料(Au-SBA-15).再以Au-SBA-15材料制备玻碳修饰电极,将血红蛋白固定于修饰电极上用循环伏安法考察其对不同浓度H_2O_2溶液的电催化反应.在固定了血红蛋白的Hb/Au-SBA-15/GC修饰电极上,H_2O_2在+0.95V处出现了氧化峰,且随着H_2O_2浓度的增大峰电流不断增加,说明金复合介孔氧化硅材料具有良好的生物兼容性,有利于血红蛋白的固定,其修饰电极对H_2O_2溶液具有一定的电催化作用.
Mesoporous SBA-15 was prepared by using Pluronic P123 triblock copolymer as structure-directing agents and Au-modified mesoporous SBA-15 （Au-SBA-15） was synthesized by a Deposi- tion-Precipitation methods. The surface of glass carbon was modified with Au-SBA-15 material （named Au-SBA-15/GC electrode）, then hemoglobin （Hb） was immobilized on Au-SBA-15/GC electrode （named Hb/Au- SBA-15/GC electrode）. The Hb/Au-SBA-15/GC electrode was applied to electrochemical determination of different concentration of H202 solution. An oxidation peak at 0.95 V was observed, and the peak current was found to be increased with H2O2 concentration increasing. The results indicate that the Hb/Au-SBA-15/GC modified electrode exhibited certain electrocatalytic activity.