文献类型：期刊文献

英文题名：Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and electrohydrodynamic flow

作者：Ahmad, Z.[1];Zhang, H. B.[2];Farook, U.[1];Edirisinghe, M.[1];Stride, E.[1];Colombo, P.[1,3,4]

机构：[1]UCL, Dept Mech Engn, London WC1E 7JE, England;[2]E China Univ Sci & Technol, Sch Mech & Power Engn, Shanghai 200237, Peoples R China;[3]Univ Padua, Dept Mech Engn & Mat Sci, I-35122 Padua, Italy;[4]Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA

年份：2008

卷号：5

期号：27

起止页码：1255

外文期刊名：JOURNAL OF THE ROYAL SOCIETY INTERFACE

收录：;EI(收录号：20083511486626);WOS:【SCI-EXPANDED(收录号:WOS:000258530600011)】；

基金：We are grateful to the archaeology and chemistry departments at University College London for use of their SEM and TEM equipments, respectively. We also acknowledge the EPSRC grant EP/E045839 and Royal Academy of Engineering for supporting this work. Collaboration between UCL and the University of Padua was funded by the Royal Society and we wish to acknowledge the exchange visits made possible by this grant.

语种：英文

外文关键词：electrohydrodynamic; biomedical; layered structures

摘要：In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare double-layered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.