文献类型：期刊文献

英文题名：Tracking Dual-Pathway Self-Assembly via Butterfly-Motion-Based Molecular Fragment Conformational Transformation in Aqueous Homopolypeptides

作者：Wu, Yifan[1,2];Shen, Ruizi[1,2];Wang, Qiaochun[1,2];Chen, Xuanying[1,2,3];Zhang, Zhiyun[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Shanghai Univ Elect Power, Shanghai Key Lab Mat Protect & Adv Mat Elect Power, Shanghai 200090, Peoples R China

年份：2025

卷号：31

期号：72

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20254619518812);WOS:【SCI-EXPANDED(收录号:WOS:001613359800001)】；

基金：This research was made possible as a result of a generous grant from NSFC/China (22335004, 22405087, 22475067 and 22175063), Science and Technology Commission of Shanghai Municipality (grant No.24DX1400200), the Programme of Introducing Talents of Discipline to Universities (B16017).

语种：英文

外文关键词：CPL; homopolypeptide; monitoring; peptides; polychromatic fluorescent; self-assembly

摘要：Despite the inherent chirality of peptides, the development of peptide-based luminescent nanomaterials has been impeded by weak fluorescence and unclear self-assembly mechanisms. Herein, we report a straightforward strategy to direct supramolecular assembly by end-functionalizing homopolypeptides with a vibration-induced emission (VIE) motif. This system exhibits dual-pathway self-assembly, enabling real-time monitoring of the assembly process via ratiometric fluorescence changes. Depending on the solvent used, the homopolypeptides self-organize into either nanotoroids or nanorods, which display distinct CPL properties: the nanotoroids exhibit strong CPL activity, whereas the nanorods are CPL-silent. This work not only establishes a versatile platform for constructing efficient aqueous CPL-active nanomaterials but also elucidates the correlation between supramolecular morphology and chiroptical output, paving the way for the rational design of biocompatible chiral luminescent systems.