文献类型：期刊文献

英文题名：Naphthalimide-based fluorescent photoinduced electron transfer sensors for saccharides

作者：Liu, Shanshan[1];Bai, Hongyan[1];Sun, Qian[1];Zhang, Weibing[1];Qian, Junhong[1]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2015

卷号：5

期号：4

起止页码：2837

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20145100332964);WOS:【SCI-EXPANDED(收录号:WOS:000346188400062)】；

基金：This work was financially supported by National 973 Program (no. 2011CB910403), NSFC (no. 21235005) and Shanghai Municipal Natural Science Foundation. We thank Dr H.-Y. Tian(East China University of Science & Technology) for his kind help.

语种：英文

外文关键词：Fluorophores - Fructose - Electron transitions

摘要：The design and synthesis of two novel fluorescent sensors based on the photoinduced electron transfer (PET) mechanism for the detection of saccharides in aqueous medium is described. These sensors are based on the 4-amino-1,8-naphthalimide fluorophore, which absorbs and emits at similar to 400 nm and similar to 530 nm, respectively. By incorporating a phenylboronic acid receptor at the 4-position through a piperazine linker, high sensitivity was achieved for the sensing of saccharides. Both probes showed pHdependent fluorescence intensities, with pK(a) values of 4.8 (PET-S1) and 4.4 (PET-S2), respectively. After binding with sugars, up to 50-fold and 5-fold fluorescence enhancements for PET-S1 and PET-S2 were observed at pH 7.4, which allows them to be used under physiological conditions. The switch-on responses of both probes toward saccharides demonstrating the suppression of PET from the amino group to the fluorophore. The probes showed high sensitivity towards D-fructose and D-sorbitol. Probe PET-S1 was used to detect fructose in honey and beverages with good recovery.