文献类型：期刊文献

英文题名：A novel electrochemical sensor based on bimetallic metal organic framework-derived porous carbon for detection of uric acid

作者：Liu, Longlong[1];Liu, Liu[1];Wang, Yuli[2];Ye, Bang-Ce[1,3]

机构：[1]Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China;[2]Shihezi Univ, Affiliated Hosp 1, Sch Med, Dept Oncol, Shihezi 832008, Peoples R China;[3]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2019

卷号：199

起止页码：478

外文期刊名：TALANTA

收录：;EI(收录号：20191006585177);WOS:【SCI-EXPANDED(收录号:WOS:000465050000063)】；

基金：This work was jointly supported by the National Natural Science Foundation of China (Grants 21575089 and 21335003).

语种：英文

外文关键词：Porous carbon; Carbonization; Bimetallic zeolitic imidazolate frameworks; Electrochemical detection; Uric acid

摘要：We demonstrate a facile electrochemical sensor (CNCo/GCE) based on N,Co-doped porous carbon (CNCo) as electrode materials for detection of uric acid (UA). The porous carbon materials were prepared via the direct carbonization of bimetallic zeolitic imidazolate frameworks (BMZIFs) based on ZIF-8 and ZIF-67 with an appropriate molar ratio of Zn/Co at 900 C in an N2 atmosphere. The properties of the BMZIFs and CNCo were characterized by SEM, TEM, XRD, and XPS. The electrochemical behaviors of the CNCo-modified electrode were investigated using cyclic voltammetry (CV), impedance analysis (EIS), and differential pulse voltammetry (DPV) and showed enhanced electrochemical catalytic activity toward UA. DPV was conducted for the determination of UA with a linear range of 2.0-110 tiM and a low detection limit of 0.83 04 at an S/N = 3. Furthermore, the CNCo/GCE electrode showed good reproducibility and repeatability with RSDs of 3.07% and 3.26%, respectively. Additionally, the sensor was successfully employed to quantify UA in human serum samples with satisfactory recoveries, suggesting it is a promising candidate for biological applications.