详细信息
铁炭复合磁性载体的制备及性能测定 ( EI收录)
Preparation and Characterization of Iron-Carbon Composite Magnetically Targeted Carriers
文献类型:期刊文献
中文题名:铁炭复合磁性载体的制备及性能测定
英文题名:Preparation and Characterization of Iron-Carbon Composite Magnetically Targeted Carriers
作者:曹宏明[1];黄广建[2];宣绍峰[3];李春忠[1];王淑芬[1]
机构:[1]华东理工大学超细材料制备与应用教育部重点实验室,上海200237;[2]复旦大学附属华山医院,上海200040;[3]华东理工大学国家超细粉末工程研究中心,上海200237
年份:2007
卷号:33
期号:5
起止页码:652
中文期刊名:华东理工大学学报(自然科学版)
外文期刊名:Journal of East China University of Science and Technology
收录:CSTPCD;;EI(收录号:20074710937350);Scopus;北大核心:【北大核心2004】;CSCD:【CSCD2011_2012】;
基金:国家自然科学基金资助项目(30471682);上海市基础研究重点项目(05JC14016);国家科技部重大基础研究前期研究专项资助项目(2002CCA01100)
语种:中文
中文关键词:铁炭复合磁性载体;磁靶向;缓释
外文关键词:iron-carbon magnetic composite; magnetic targeting; controlled desorption
摘要:采用中和沉淀法对球磨法制备的Fe3O4/C初级复合磁性载体进行了表面改性,并经过固相高温还原得到了铁炭复合磁性载体。制备的载体分别用TEM、XRD、TG及TPM-7 BH仪进行了表征。考察了磁靶向药物载体的热稳定性,并对其在空气中磁性能的变化规律及其在类似人体的环境中磁性能的变化趋势进行了考察。结果表明:所制备的复合磁性载体能满足实际应用的要求。
Surface modification of the ball-mill prepared Fe304/C magnetic composites was carried out using a precipitation method. Fe/C magnetic composites were obtained by solid-state high-temperature deoxidating of the modified Fe3O4/C magnetic composites. The obtained products were characterized by transmission electron micrograph (TEM) images, X-ray diffraction (XRD) pattern, thermogravimetric analysis (TG) and grain-size distribution. The thermal stability of the drug targeting magnetic composites and the change of the magnetic properties of the composites in air and similar human inner environment were also measured. The results reveal that the properties of the prepared products can satisfy the requests of practical applications.
参考文献:
正在载入数据...
