文献类型：期刊文献

英文题名：Apatite-forming ability and mechanical properties of PTMO-modified CaO-SiO₂ hybrids prepared by sol-gel processing:: Effect of CaO and PTMO contents

作者：Miyata, N; Fuke, K; Chen, Q; Kawashita, M; Kokubo, T; Nakamura, T

机构：[1]Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 6068501, Japan;[2]E China Univ Sci & Technol, Dept Inorgan Mat, Shanghai 200237, Peoples R China;[3]Kyoto Univ, Grad Sch Med, Dept Orthopaed Surg, Sakyo Ku, Kyoto 6068507, Japan

年份：2002

卷号：23

期号：14

起止页码：3033

外文期刊名：BIOMATERIALS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000176015400026)】；

语种：英文

外文关键词：organic-inorganic hybrids; poly(tetramethylene oxide); apatite-forming ability; bioactivity; mechanical properties

摘要：Transparent monolithics of triethoxysilane end-capped poly(tetramethylene oxide) (Si-PTMO)-modified CaO-SiO2 hybrids were successfully synthesized by hydrolysis and polycondensation of Si-PTMO, tetraethoxysilane (TEOS) and calcium nitrate. As for the samples with varying (Ca(NTO3)(2))/(TEOS) molar ratios under constant ratio of (Si-PTMO)/(TEOS) of 2/3 in weight, the apatite-forming ability in a simulated body fluid (SBF) which is indicative of bioactivity, remarkably increased with increasing CaO content, although the tensile strength and Young's modulus decreased. The hybrid with (Ca(NO3)(2))/(TEOS) = 0.15 in mol formed an apatite on its surface within only I day. For this series of samples, the strain at failure which is a measure of capability for deformation of material, was found to be about 30% and almost independent of CaO content. As for the samples with varying (Si-PTMO)/(TEOS) weight ratios under constant ratio of (Ca(NO3)(2))/(TEOS) of 0.15 in mol, the strain at failure increased with increasing Si-PTMO content, but the apatite-forming ability, tensile strength and Young's modulus decreased. Thus, the synthesis of the hybrids exhibiting both high apatite-forming ability and high extensibility can be achieved by selecting suitable CaO and Si-PTMO contents. These new kind of hybrid materials may be useful as bioactive bone-repairing materials. (C) 2002 Elsevier Science Ltd. All rights reserved.