文献类型：期刊文献

中文题名：反应精馏法合成氯乙酸乙酯的工艺研究

英文题名：Synthesis of ethyl chloroacetate by reactive distillation

作者：雷文龙[1];田恒水[1];王涛[1];黄婕[1]

机构：[1]华东理工大学化工学院,上海200237

年份：2017

卷号：42

期号：6

起止页码：81

中文期刊名：天然气化工—C1化学与化工

外文期刊名：Natural Gas Chemical Industry

收录：北大核心:【北大核心2014】；CSCD:【CSCD_E2017_2018】；

语种：中文

中文关键词：氯乙酸乙酯;强酸性阳离子交换树脂;反应精馏;带水剂

外文关键词：ethyl chloroacetate; strong-acid cation exchange resin; reactive distillation; water-carrying agent

摘要：以氯乙酸和无水乙醇为原料,环己烷为带水剂,采用反应精馏的方法合成氯乙酸乙酯。考察了催化剂种类、催化剂用量、原料配比、环己烷用量以及有效板数对反应的影响。结果表明,较佳的反应条件为:D8099-T强酸性阳离子交换树脂为催化剂,用量为氯乙酸质量的1.00%,n(氯乙酸)∶n(无水乙醇)=1∶3,环己烷用量为80m L/mol氯乙酸,有效板数为14。在该反应条件下,氯乙酸的转化率为100%,氯乙酸乙酯的收率为97.77%。
The synthesis of ethyl chloroacetate from chloroacetic acid and ethyl alcohol by reactive distillation using cyclohexane as water-carrying agent was studied. The effects of catalyst types and dosage, reactants ratio, cyclohexane amount and tray number on reaction were investigated. The results indicate that the optimal reaction conditions are as follows： D8099-T strong- acid cation resin as catalyst, mass ratio of catalyst to chloroacetic acid of 1.0%, molar ratio of chloroacetic acid to ethanol of 1 ： 3, cyclohexane 80 mL per mole chloroacetic acid, and tray number of 14. Under above conditions, the yield of ethyl chloroacetate and conversion of chloroacetic acid reached 97.77% and 100%, respectively.