文献类型：期刊文献

英文题名：Rhodium(III)-Catalyzed Direct C-2 Olefination of Unactivated Indoles Utilizing OH/NH2 as Directing Group

作者：Tang, Chen-Yu[1,2];Tao, Yuan[1,2];Wu, Xin-Yan[1,2];Sha, Feng[1,2]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2014

卷号：356

期号：2-3

起止页码：609

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000332000200045)，CCR-EXPANDED(收录号:WOS:000332000200045)】；

基金：We are grateful for the financial support from National Natural Science Foundation of China (Project Nos. 21102043), the China Postdoctoral Science Foundation (Project Nos. 20110490070, and 2012T50401) and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：directing groups; hydroxy group; indoles; olefination; rhodium

摘要：Oxidative C-2 olefination of indoles/pyrrole via rhodium(III)-catalyzed direct CH bond activation is reported. Phenolic OH and aniline NH2 units were revealed to be effective chelating groups to activate the aryl CH bond. The reactions proceeded with excellent selectivity and high functional group tolerance, furnishing 2-vinylindoles/2-vinylpyrroles in good yields.