文献类型：期刊文献

英文题名：Photoresponsive DNA materials and their applications

作者：Wang, Chen[1];O'Hagan, Michael P.[1];Li, Ziyuan[2];Zhang, Junji[2];Ma, Xiang[2];Tian, He[2];Willner, Itamar[1]

机构：[1]Hebrew Univ Jerusalem, Ctr Nanosci & Nanotechnol, Inst Chem, IL-91904 Jerusalem, Israel;[2]East China Univ Sci & Technol, Frontiers Ctr Mat & Dynam Chem, Sch Chem & Mol Engn,Joint Int Res Lab Precis Chem, Feringa Nobel Prize Scientist Joint Res Ctr,Key L, Shanghai 200237, Peoples R China

年份：2022

卷号：51

期号：2

起止页码：720

外文期刊名：CHEMICAL SOCIETY REVIEWS

收录：;EI(收录号：20220611586848);WOS:【SCI-EXPANDED(收录号:WOS:000739566400001)】；

基金：C. W. acknowledges funding support from the Israel Science Foundation. M. P. O. acknowledges the support of The Council for Higher Education in Israel, and the Israel Academy of Sciences and Humanities for a post-doctoral fellowship. Z. L. acknowledges funding support from the Shanghai Sailing Program (20YF1410300) and the China Postdoctoral Science Foundation (2020M671017). J. Z. acknowledges funding support from the NSFC (22122803, 21878086) and the Shanghai Rising-Star Program (19QA1402500). X. M. and H. T. acknowledge funding support from the NSFC (22020102006). I. W. acknowledges funding support from the Israel Science Foundation.

语种：英文

外文关键词：Photosensitizers - Scaffolds - Biomolecules

摘要：Photoresponsive nucleic acids attract growing interest as functional constituents in materials science. Integration of photoisomerizable units into DNA strands provides an ideal handle for the reversible reconfiguration of nucleic acid architectures by light irradiation, triggering changes in the chemical and structural properties of the nanostructures that can be exploited in the development of photoresponsive functional devices such as machines, origami structures and ion channels, as well as environmentally adaptable 'smart' materials including nanoparticle aggregates and hydrogels. Moreover, photoresponsive DNA components allow control over the composition of dynamic supramolecular ensembles that mimic native networks. Beyond this, the modification of nucleic acids with photosensitizer functionality enables these biopolymers to act as scaffolds for spatial organization of electron transfer reactions mimicking natural photosynthesis. This review provides a comprehensive overview of these exciting developments in the design of photoresponsive DNA materials, and showcases a range of applications in catalysis, sensing and drug delivery/release. The key challenges facing the development of the field in the coming years are addressed, and exciting emergent research directions are identified.