文献类型：期刊文献

中文题名：光控水凝胶的构筑及在生物医药领域的应用

英文题名：Construction of Photo-controlled Hydrogels and Their Applications in Biomedical Fields

作者：华鑫[1];包春燕[1];林秋宁[1];朱麟勇[1]

机构：[1]华东理工大学化学与分子工程学院上海市功能性材料化学重点实验室,上海200237

年份：2017

卷号：35

期号：4

起止页码：379

中文期刊名：影像科学与光化学

外文期刊名：Imaging Science and Photochemistry

收录：CSTPCD;;Scopus;北大核心:【北大核心2014】；CSCD:【CSCD_E2017_2018】；

基金：国家自然科学基金项目(21472044;21373084;21425311)资助

语种：中文

中文关键词：水凝胶;光响应;光化学反应;生物应用

外文关键词：hydrogel; photo-responsive; photochemistry reaction; biological application

摘要：水凝胶由于具有优越的保水性、良好的生物相容性和可降解性,被认为是最接近人体组织的生物医用材料。通过构建环境敏感水凝胶可以高度拟合生物组织的微环境,实现其在组织工程与再生医学领域的应用。由于光具有非物理接触和时空分辨等优势,利用光调控技术可实现水凝胶微环境的精确构筑与调控。本文重点介绍了近年来光控水凝胶的构筑,以及在生物医学和材料领域的应用进展。
Hydrogels are the closest biomaterials to the human tissue for their high water retention, goodbiocompatibility, and fast biodegradability. The construction of environment-sensitive hydrogels can highlysimulate the microenvironment of biological tissue, realizing the applications in tissue engineering andregenerative medicine fields. Due to the advantages of non-invasive manipulation and high spatiotemporalresolution of light control technology, it provides an efficient way to precisely construct and control themicroenvironment of hydrogel as theextracellular matrix （ECMs） , which has become one of the researchhotspots in biomedicine and tissue engineer field. This review summarizes the construction of photo-responsive hydrogels and their applications in the field of biological medicine and material research in recent years.