文献类型：期刊文献

英文题名：Direct oxidation of β-aryl substituted aldehydes to α,β-unsaturated aldehydes promoted by an o-anisidine-Pd(OAc) 2 Co-catalyst

作者：Liu, Jie[1]; Zhu, Jin[1]; Jiang, Hualiang[1,3]; Wang, Wei[1,2,3]; Li, Jian[1]

机构：[1] School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China; [2] Department of Chemistry and Chemical Biology, University of New Mexico, MSC03 2060, Albuquerque, NM 87131-0001, United States; [3] Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China

年份：2009

卷号：4

期号：11

起止页码：1712

外文期刊名：Chemistry - An Asian Journal

收录：EI(收录号：20100212624288)

语种：英文

外文关键词：Catalytic oxidation - Cost effectiveness - Palladium

摘要：An o-anisidine-Pd(OAc)2 catalytic system for the direct co-catalytic Saegusa oxidation of β-aryl substituted aldehydes to α,β-unsaturated aldehydes has been developed. The use of o-anisidine in place of (S)-diphenylprolinol made the process more simply and cost-effective. The process not only features the use of unmodified aldehydes rather than enol silyl ethers, but also gives moderate to good yields (44-72%). ? 2009 Wiley-VCH Verlag GmbH & Co. KGaA.