文献类型：期刊文献

英文题名：Palladium-Catalyzed Site-Selective Benzocyclization of Naphthoic Acids with Diaryliodonium Salts: Efficient Access to Benzanthrones

作者：Xue, Chenwei[1,2];Wang, Limin[1,2];Han, Jianwei[1,2,3]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai 200032, Peoples R China

年份：2020

卷号：85

期号：23

起止页码：15406

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20205209668202);WOS:【SCI-EXPANDED(收录号:WOS:000598137400051)】；

基金：The work was supported by the Natural Science Foundation of Shanghai (20ZR1413500), the National Key Research and Development Program (2016YFA0200302), the National Nature Science Foundation of China (NSFC 21772039 and 21472213), the Croucher Foundation (Hong Kong) in the form of a CAS-Croucher Foundation Joint Laboratory Grant, the Fundamental Research Funds for the Central Universities, Shanghai Municipal Science and Technology Major Project (grant no. 2018SHZDZX03), and the Programme of Introducing Talents of Discipline to Universities (B16017). We thank Mr. Cheng Pan for conducting some experiments.

语种：英文

外文关键词：Catalysts - Salts - Catalysis - Palladium

摘要：Dual activation of both C-I and vicinal C-H bonds of diaryliodonium salts allowing for diarylation is a subject of rapid construction of pi-extended frameworks. Here, we report palladium-catalyzed cascade of C-8-arylation/intramolecular Friedel-Crafts acylation of a-naphthoic acids in the synthesis of benzanthrone derivatives. The step-economical protocol tolerates various substrates, which resulted in a potential molecular library for developing functional polycyclic scaffolds. The approach relies on the synergistic action of strong acid with palladium catalysts to form two bonds in a one-pot procedure.