文献类型：期刊文献

英文题名：Regioselective and Enantioselective Cu(II)-Catalyzed 1,4-Conjugate Addition of Diethylzinc Reagent to Nitrodienes

作者：Rexiti, Rukeya[1,2];Zhang, Zhen-Guo[1,2];Lu, Jian[1,2];Sha, Feng[1,2];Wu, Xin-Yan[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2019

卷号：84

期号：3

起止页码：1330

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20190506441131);WOS:【SCI-EXPANDED(收录号:WOS:000457947800020)，CCR-EXPANDED(收录号:WOS:000457947800020)】；

基金：We are grateful for the financial support from the Science and Technology Commission of Shanghai Municipality (15ZR1409200).

语种：英文

外文关键词：Enantioselectivity - Catalysis - Copper compounds

摘要：The regioselective and enantioselective Cu(II)-catalyzed 1,4-conjugate addition of diethylzinc reagent to nitrodienes is described. With 0.25 mol % of Cu(OAc)(2) and chiral amidophosphine ligand L3, the 1,4-addition products were produced with a complete regioselectivity, high yields (81-98%), and excellent enantioselectivities (87-97% ee) in a short reaction time.