文献类型：期刊文献

英文题名：Palladium-catalyzed acylative cross-coupling of amides with diarylborinic acids and sodium tetraarylborates

作者：Li, Xijing[1];Zou, Gang[1]

机构：[1]E China Univ Sci & Technol, Dept Fine Chem, Shanghai, Peoples R China

年份：2015

卷号：794

起止页码：136

外文期刊名：JOURNAL OF ORGANOMETALLIC CHEMISTRY

收录：;EI(收录号：20152901047006);WOS:【SCI-EXPANDED(收录号:WOS:000360084000019)】；

基金：We are grateful for financial support provided by the National Science Foundation of China (No. 21472041).

语种：英文

外文关键词：Acylative Suzuki coupling; Active amides; Diarylborinic acids; Sodium tetraarylborates; Palladium

摘要：A general and efficient acylative Suzuki coupling of active amides with diarylborinic acids has been achieved by using 1 mol% Pd(PCy3)(2)Cl-2/0.6 mol% PCy3 as catalyst system taking advantage of modifiable reactivities of acyl-nitrogen bonds of amides. Both electronic and steric influences from either aryl or acyl counterparts on the coupling proved to be negligible or small. A variety of aryl ketones including sterically hindered ones could be synthesized by the coupling of diarylborinic acids in good to excellent yields. Sodium tetraarylborates could also be used as high atom-economy aryl source in the palladium-catalyzed cross-coupling with active amides. (C) 2015 Elsevier B.V. All rights reserved.