文献类型：期刊文献

英文题名：Development of Ion Chemosensors Based on Porphyrin Analogues

作者：Ding, Yubin[1,2,3];Zhu, Wei-Hong[1,2];Xie, Yongshu[1,2]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[3]Nanjing Univ, Coll Engn & Appl Sci, Dept Biomed Engn, Nanjing 210093, Jiangsu, Peoples R China

年份：2017

卷号：117

期号：4

起止页码：2203

外文期刊名：CHEMICAL REVIEWS

收录：;EI(收录号：20170903383356);WOS:【SCI-EXPANDED(收录号:WOS:000394829000002)】；

基金：This work was supported by the Science Fund for Creative Research Groups (21421004), National Basic Research 973 Program (2013CB733700), NSFC/China (21472047, 91227201), the Oriental Scholarship, and the Programme of Introducing Talents of Discipline to Universities (B16017). Y.D. thanks the Natural Science Foundation of Jiangsu Province (BK20140593) and Open Funds of the State Key Laboratory for Chemo/Biosensing and Chemometrics (2014002) for financial support. We thank Professor Hui Wei at NJU for insightful discussions.

语种：英文

外文关键词：Hydrogen bonds - Physiology - Biocompatibility - Metals - Infrared devices - Porphyrins - Metal ions

摘要：Sensing of metal ions and anions is of great importance because of their widespread distribution in environmental systems and biological processes. Colorimetric and fluorescent chemosensors based on organic molecular species have been demonstrated to be effective for the detection of various ions and possess the significant advantages of low cost, high sensitivity, and convenient implementation. Of the available classes of organic molecules, porphyrin analogues possess inherently many advantageous features, making them suitable for the design of ion chemosensors, with the targeted sensing behavior achieved and easily modulated based on their following characteristics: (1) NH moieties properly disposed for binding of anions through cooperative hydrogen-bonding interactions; (2) multiple pyrrolic N atoms or other heteroatoms for selectively chelating metal ions; (3) variability of macrocycle size and peripheral substitution for modulation of ion selectivity and sensitivity; and (4) tunable near-infrared emission and good biocompatibility. In this Review, design strategies, sensing mechanisms, and sensing performance of ion chemosensors based on porphyrin analogues are described by use of extensive examples. Ion chemosensors based on normal porphyrins and linear oligopyrroles are also briefly described. This Review provides valuable information for researchers of related areas and thus may inspire the development of more practical and effective approaches for designing high-performance ion chemosensors based on porphyrin analogues and other relevant compounds.