文献类型：期刊文献

英文题名：Synthesis of 1,4-benzoxazine derivatives from α-aminocarbonyls under transition-metal-free conditions

作者：Hao, Liqiang;Wu, Gaorong;Wang, Yangyang;Xu, Xiaobo;Ji, Yafei[1]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, 130 Meilong Rd, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2023

卷号：47

期号：20

起止页码：9527

外文期刊名：NEW JOURNAL OF CHEMISTRY

收录：;EI(收录号：20231814032351);WOS:【SCI-EXPANDED(收录号:WOS:000972844800001)，CCR-EXPANDED(收录号:WOS:000972844800001)】；

基金：We gratefully thank the National Natural Science Foundation of China (No. 21676088) for financial support.

语种：英文

外文关键词：Organic solvents - Transition metals

摘要：Herein, we report a one-pot tandem reaction for the synthesis of 1,4-benzoxazine derivatives with up to 83% yield. The present protocol, using ethanol as a solvent and avoiding the use of transition metal catalysts, exhibits a wide range of substrate scope and functional group tolerance. This novel, mild and efficient method is highly promising for constructing 1,4-benzoxazine derivatives.