文献类型：期刊文献

英文题名：Molecular probe design via the "covalent-assembly" principle

作者：Luo, Xiao[1];Gu, Luyan[2];Qian, Xuhong[2];Yang, Youjun[2]

机构：[1]East China Normal Univ, Sch Chem & Mol Engn, Dongchuan Rd 500, Shanghai 200241, Peoples R China;[2]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2020

卷号：56

期号：64

起止页码：9067

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20204009252849);WOS:【SCI-EXPANDED(收录号:WOS:000558045700002)】；

基金：This work is supported by the China Postdoctoral Science Foundation (2019M651427) and the National Natural Science Foundation of China (No. 21572061, 21822805, and 21908065).

语种：英文

外文关键词：Chemical analysis - Diagnosis

摘要：Fluorescent probes find widespread applications in chemical analysis, biosensing, and disease diagnosis and are also the cornerstones of many cutting-edge biotechnologies. Yet, the numerous probes developed thus far are actually based on a handful of probe design principles. In this article, we wish to summarize the recent progress of the field toward the use of a novel "covalent-assembly" principle for probe design.