文献类型：期刊文献

英文题名：A Novel Bifunctional Sulfonamide Primary Amine-Catalyzed Enantioselective Conjugate Addition of Ketones to Nitroolefins

作者：Xue, Fei[1];Zhang, Shilei[1];Duan, Wenhu[1,2];Wang, Wei[1,3]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Dept Pharmaceut Sci, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Grad Sch, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;[3]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2008

卷号：350

期号：14-15

起止页码：2194

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000260760700007)】；

基金：This work was supported by Shanghai Basic Research Project from the Shanghai Science and Technology Commission (Grants 06JC14080) and start-tip fund from School of Pharmacy, East China University of Science & Technology.

语种：英文

外文关键词：conjugate addition; ketones; nitroolefins; organocatalysis; sulfonamide primary amine

摘要：The enantioselective conjugate addition of a variety of ketones to nitroolefins has been developed. The process is efficiently catalyzed by a novel bifunctional sulfonamide primary amine in good yields and with good levels of enantioselectivity.