文献类型：期刊文献

英文题名：Single molecule analysis by biological nanopore sensors

作者：Ying, Yi-Lun[1];Cao, Chan[1];Long, Yi-Tao[1]

机构：[1]E China Univ Sci & Technol, Dept Chem, Shanghai, Peoples R China

年份：2014

卷号：139

期号：16

起止页码：3826

外文期刊名：ANALYST

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000339538500001)】；

基金：This work was supported by the National Base Research 973 Program (2013CB733700) and National Science Fund of China (21327807). Y.-T.L. is supported by the National Science Fund for Distinguished Young Scholars of China (21125522). Y.-L.Y. thanks the Sino-UK Higher Education Research Partnership for PhD Studies.

语种：英文

摘要：Nanopore sensors provide a highly innovative technique for a rapid and label-free single molecule analysis, which holds a great potential in routing applications. Biological nanopores have been used as ultra-sensitive sensors over a wide range of single molecule analysis including DNA sequencing, disease diagnosis, drug screening, environment monitoring and the construction of molecule machines. This mini review will focus on the current strategies for the identification and characterization of an individual analyte, especially based on our recent achievements in biological nanopore biosensors.