文献类型：期刊文献

英文题名：A high yield method for the direct amidation of long-chain fatty acids

作者：Wang, Man-Yu[1,2];Gang, Hong-Ze[1,2];Zhou, Lei[1,2];Liu, Jin-Feng[1,2];Mu, Bo-Zhong[1,2];Yang, Shi-Zhong[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Appl Chem, Shanghai 200237, Peoples R China

年份：2020

卷号：52

期号：2

起止页码：99

外文期刊名：INTERNATIONAL JOURNAL OF CHEMICAL KINETICS

收录：;EI(收录号：20195007815396);WOS:【SCI-EXPANDED(收录号:WOS:000500060900001)】；

基金：National Key Research and Development Program of China, Grant/Award Number: 2017YFB0308900; National Natural Science Foundation of China, Grant/Award Number: 51574125; Fundamental Research Funds for the Central Universities of China, Grant/Award Number: 50321101917017.

语种：英文

外文关键词：3; 4; 5-trifluorophenylboronic acid; amides; direct amidation; long-chain fatty acids; long-chain phenyl fatty acids

摘要：The amidation of long-chain fatty acids is the key step for preparing surfactants with excellent interfacial activity. Gas chromatography-mass spectrometry was employed to detect the reactants and products in the direct amidation reactions. The conversion and the concentration of the amides in the reaction process were also investigated to determine the best catalyst, the reaction rate constants, and activation energy. It was identified that the amidation reaction of the long-chain phenyl fatty acid was a zero-order reaction and 3,4,5-trifluorophenylboronic acid was the most effective catalyst by which the activation energy reduced to 55.79 kJ/mol from 95.44 kJ/mol. The method can be applied to other long-chain fatty acids, saturated or unsatureated. The turning-over-temperature was 156 degrees C, over which high yields can be achieved without any catalyst. These provide a reference for the preparation of long-chain fatty acid amides.