文献类型：期刊文献

英文题名：Dual quenching strategy for sensitive detection of toxic thiolphenols based on a NIR-illuminant platform with a large Stokes shift

作者：Wang, Kai[1,2];Zhao, Cheng-Xi[1,2];Leng, Tao-Hua[3];Wang, Cheng-Yun[1,2];Lu, Yun-Xiang[1,2];Shen, Yong-Jia[1,2];Zhu, Wei-Hong[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Shanghai Inst Qual Inspect & Tech Res, Natl Food Qual Supervis & Inspect Ctr Shanghai, Shanghai 200233, Peoples R China

年份：2018

卷号：151

起止页码：194

外文期刊名：DYES AND PIGMENTS

收录：;EI(收录号：20181304955006);WOS:【SCI-EXPANDED(收录号:WOS:000427331900026)】；

基金：The authors are grateful to financial support from Natural Science Foundation of Shanghai (16ZR1408000), and the National Key Program of China (No. 2016YFA0200302).

语种：英文

外文关键词：Isophorone-based dye; Near-infrared fluorescence; Large Stokes shift; Thiophenol; DFT calculations; Fluorescent imaging

摘要：In view of thiophenol contaminants and their adverse effects in environment, it is valuable to develop an effective probe for thiophenols. Based on a large Stokes shift (126 nm) NIR-illuminant platform (Compound 2), we developed a colorimetric and "off-on" near-infrared (NIR) fluorescent probe (NIRP) to selectively discriminate thiophenols from various analytes including aliphatic thiols. NIRP is dually quenched (ICT blocked quenching and PET quenching), thus achieving large signal-to-noise ratio and high sensitivity for thiophenol detection. For the first time, the unique NIR-illuminant phenomenon of 2' and the d-PET quenching process on NIRP are revealed by the density functional theory (DFT) calculations. Moreover, we demonstrate the practical applications of NIRP, including the quantitative thiophenol detection in environmental water samples and NIR fluorescent imaging of thiophenol in HeLa cells.