文献类型：期刊文献

英文题名：Naphthalimide-based fluorescent 'turn-off' probes for palladium ions: structure-activity relationships

作者：Chen, Han[1];Wang, Hao[1];Xu, Junqiang[1];Xie, Xinyang[1];Zhang, Weibing[1];Qian, Junhong[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2025

卷号：17

期号：25

起止页码：5286

外文期刊名：ANALYTICAL METHODS

收录：;EI(收录号：20252518640065);WOS:【SCI-EXPANDED(收录号:WOS:001516964200001)】；

基金：This work was financially supported by National Key Research and Development Program of China (2022YFD1700800).

语种：英文

外文关键词：Palladium compounds - Probes

摘要：Palladium is extensively applied in many high-tech industries, but excessive residue in the environment is harmful to humans. Therefore, it is important to develop effective analysis methods for palladium ions. In this work, six naphthalimide-based fluorescent probes NPA-NPF were synthesized with ethylenediamine derivatives as the receptors. The experimental results show that the probes bearing flexible ethylenediamine exhibited excellent sensitivity and selectivity toward Pd2+, whereas NPC with rigid piperazine as the receptor displayed minimum response to Pd2+. The introduction of biotin and indomethacin enabled NPE and NPF to selectively bioimage Pd2+ in living cancer cells. Job's plot results revealed that Pd2+ formed a 1 : 1 complex with the probes having one receptor (NPA-NPC) or a 2 : 1 complex with those bearing two receptors (NPD and NPE).