文献类型：期刊文献

英文题名：A highly efficient catalytic system for cross-coupling of aryl chlorides and bromides with malononitrile anion by palladium carbene complexes

作者：Gao, CW; Tao, XC; Qian, YL; Huang, JL

机构：[1]E China Univ Sci & Technol, Organomet Chem Lab, Shanghai 200237, Peoples R China

年份：2003

期号：12

起止页码：1444

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000183215200060)，CCR-EXPANDED(收录号:WOS:000183215200060)】；

语种：英文

摘要：Six imidazolium chlorides (1-6) as precursors of 1,3-diaryl substituted N-heterocyclic carbene ligands were synthesized and evaluated in palladium-catalyzed cross-coupling reactions of aryl chlorides and bromides with malononitrile in the presence of NaH. Among them, 1,3-bis(2,4,6-triethylphenyl)imidazolium chloride (5) and 1,3-bis(2,4,6-triisopropylphenyl)imidazolium chloride (6) are novel. The catalytic system combining Pd(0) with imidazolium salts 4, 5 and 6 with bulky aryl groups in pyridine is found to be superior over others and afforded alpha-arylmalononitriles in high yields when employing a wide variety of substrates.