详细信息

Acid-sensitive splitting-decomposable connecting unit for amphiphilic block copolymer used for self-assembly micelle used as drug transport agent, has ethoxy group-containing structural unit    

文献类型:专利

英文题名:Acid-sensitive splitting-decomposable connecting unit for amphiphilic block copolymer used for self-assembly micelle used as drug transport agent, has ethoxy group-containing structural unit

作者:LI Q;GONG B;WU X;TANG D;SHEN Y;ZHUANG Y;ZHU F

机构:[1]UNIV EAST CHINA SCI&TECHNOLOGY;[2]UNIV SHANGHAI JIAOTONG;[3]UNIV EAST CHINA SCI & TECHNOLOGY

申请号:CN103012771-A

申请日:2012-11-07

公开日:2013-04-03

语种:英文

收录:DERWENT

摘要:NOVELTY - An acid-sensitive splitting-decomposable connecting unit has ethoxy group-containing structural unit (I). USE - Acid-sensitive splitting-decomposable connecting unit for amphiphilic block copolymer used for self-assembly micelle used as drug transport agent (claimed). ADVANTAGE - The acid-sensitive splitting-decomposable connecting unit effectively enables splitting decomposition under acid condition, and is efficiently connected with hydrophilic compound and hydrophobic compound to obtain amphiphilic block copolymer. The acid-sensitive splitting-decomposable connecting unit is easily produced at mild reaction conditions at high yield. DETAILED DESCRIPTION - An acid-sensitive splitting-decomposable connecting unit has ethoxy group-containing structural unit of formula (I). m=1 or 2; n=0-44;and X,Y'=Br, NH2, N3 or OH.

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