文献类型：期刊文献

英文题名：Polymersomes with aggregation-induced emission based on amphiphilic block copolypeptoids

作者：Tao, Xinfeng[1,2];Chen, Hui[2];Trepout, Sylvain[3,4];Cen, Jiayu[5];Ling, Jun[5];Li, Min-Hui[2,6]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab Adv Polymer Mat, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China;[2]PSL Univ Paris, CNRS, Inst Rech Chim Paris, Chim ParisTech,UMR8247, 11 Rue Pierre & Marie Curie, F-75005 Paris, France;[3]PSL Univ Paris, Inst Curie, INSERM U1196, F-91405 Orsay, France;[4]CNRS UMR9187, F-91405 Orsay, France;[5]Zhejiang Univ, MOE Key Lab Macromol Synth & Functionalizat, Dept Polymer Sci & Engn, Hangzhou 310027, Zhejiang, Peoples R China;[6]Beijing Univ Chem Technol, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, 15 North Third Ring Rd, Beijing 100029, Peoples R China

年份：2019

卷号：55

期号：90

起止页码：13530

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000496189400004)】；

基金：Financial support from French National Research Agency (ANR-16-CE29-0028) and the National Natural Science Foundation of China (21674091) is acknowledged. We thank Prof. Ben Zhong Tang (Hong Kong University of Science and Technology) for fruitful discussions. We thank Prof. Zhengwei Mao (Zhejiang University) for cytotoxicity analysis, and Dr Chao Deng (Zhejiang University) for quantum yield measurement. The authors thank the PICT-Ibisa for providing access to the cryo-EM facility at Institut Curie in Orsay.

语种：英文

摘要：Biocompatible polymersomes are prepared from amphiphilic block copolypeptoids with aggregation-induced emission, where the hydrophobic block P(TPE-NAG) is a tetraphenylethylene (TPE)-modified poly(N-allylglycine) and the hydrophilic block is polysarcosine. These nanoparticles are non-cytotoxic and show strong fluorescence emission in aqueous solution.