文献类型：期刊文献

英文题名：Hemilabile-coordinated copper promoted amination of aryl halides with ammonia in aqueous ethylene glycol under atmosphere pressure

作者：Guo, Zhennue[1];Guo, Jiayi[1];Song, Ying[1];Wang, Limin[1];Zou, Gang[1]

机构：[1]E China Univ Sci & Technol, Dept Fine Chem, Shanghai 200237, Peoples R China

年份：2009

卷号：23

期号：4

起止页码：150

外文期刊名：APPLIED ORGANOMETALLIC CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000264997800003)】；

基金：We thank the National Natural Science Foundation of China (20402006) and ECUST for financial support.

语种：英文

外文关键词：copper; amination; aryl halides; atmosphere pressure; water

摘要：Direct amination of aryl iodides and bromides with ammonia under 1 atm pressure has been effected using in situ-generated hemilabile coordinated copper(l) species from copper(l) halides or copper metal in aqueous ethylene glycol, producing primary aromatic amines in good yields. Ammonia pressure and water were found to accelerate the copper-mediated reaction while strong chelating ligands showed a suppression effect. A rationale for the copper-mediated amination of aryl halides with ammonia is given based on a double-face role of chelating effect. Copyright (C) 2009 John Wiley & Sons, Ltd.