文献类型：期刊文献

英文题名：Taking orders from light: progress in photochromic bio-materials

作者：Zhang, Junji;Wang, Jiaxing;Tian, He[1]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2014

卷号：1

期号：2

起止页码：169

外文期刊名：MATERIALS HORIZONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000348073000002)】；

基金：This work has been supported by NSFC/China, National Basic Research 973 Program (2013CB733700). Thanks are extended to all co-workers working on photochromic materials in our lab.

语种：英文

摘要：Photochromic materials are a family of compounds which undergo photo-reversible transformations between two different isomers with distinct physical and chemical properties. Most smart photochromic materials have been exploited in research areas such as electro-optical functional materials, while recently their applications have extended to novel bio-materials. Biological systems, such as tissue/cellular imaging, nucleotides, peptides, ion channels, etc., have emerged as a revolutionary research frontier for photochromic materials since both covalent coupling and non-covalent interactions with bio-molecules have been achieved. This review commences with a brief description of exciting progress in this field, and describes strategies for using photochromic functional molecules from bio-sensing and cell imaging to optical manipulation of bio-macromolecules (nucleotides, peptides, ion channels, GFP, etc.). Further development of these photo-switches as well as remaining challenges are also discussed and put in prospect.