文献类型：期刊文献

英文题名：Zinc induced polyelectrolyte coacervate bioadhesive and its transition to a self-healing hydrogel

作者：Wang, Weina[1,2];Xu, Yisheng[1];Li, Ang[1];Li, Tao[1];Liu, Miaomiao[1];von Klitzing, Regine[2];Ober, Christopher K.[3];Kayitmazer, A. Basak[4];Li, Li[1];Guo, Xuhong[1,5,6]

机构：[1]E China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]Tech Univ Berlin, Stranski Lab Phys & Theoret Chem, D-10623 Berlin, Germany;[3]Cornell Univ, Dept Mat Sci & Engn, Ithaca, NY 14853 USA;[4]Bogazici Univ, Dept Chem, TR-34342 Istanbul, Turkey;[5]Shihezi Univ, Key Lab Mat Oriented Chem Engn Xinjiang Uygur Aut, Xinjiang 832000, Peoples R China;[6]Shihezi Univ, Engn Res Ctr Mat Oriented Chem Engn Xinjiang Bing, Xinjiang 832000, Peoples R China

年份：2015

卷号：5

期号：82

起止页码：66871

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20153301170176);WOS:【SCI-EXPANDED(收录号:WOS:000359251600044)】；

基金：Yisheng Xu and Xuhong Guo acknowledge the financial support from the National Natural Science Foundation of China (No. 51273063, 21476143, and 21306049), the Fundamental Research Funds for the Central Universities, the higher school specialized research fund for the doctoral program (222201313005 and 222201314029), 111 Project Grant (B08021), the Open Project of State Key Laboratory of Chemical Engineering (SKL-ChE-14C01) and Firmenich. Weina Wang acknowledges the China Scholarship Council.

语种：英文

外文关键词：Chelation - Tissue engineering - Polyelectrolytes - Phenols - Self-healing materials - Zinc - Tissue - Hydrogels

摘要：To mimic the underwater adhesion of marine mussels, a bioadhesive has been prepared with a poly(acrylic acid) backbone functionalized with 30% catechol appendants. The polyelectrolyte chains can be reversibly crosslinked through metal chelation and irreversibly gelled by oxidative crosslinking. Surprisingly, the reported "poor" metal chelator Zn2+ not only imparts this injectable adhesive with superior adhesion after the formation of coacervation compared to the one chelated by a stronger metal crosslinker (e.g. Fe3+), but also generates good mechanical performance of the self-healing hydrogel after the oxidation of catechol groups with a pH trigger. Such a pH-responsive material with strong adhesion and good self-healing property at different conditions could be an ideal candidate in biomedical adhesion and tissue engineering.