文献类型：期刊文献

中文题名：Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401

英文题名：Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401

作者：Yu Cai He[a][1];Jian He Xu[a]&Email:jianhexu@ecust.edu.cn[1];Yi Xu[a][1];Li Ming Ouyang[a][1];Jiang Pan[a][1];

机构：[1][a]Laboratory of Biocatalysis and Bioprocessing, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China;

年份：2007

卷号：18

期号：6

起止页码：677

中文期刊名：Chinese Chemical Letters

外文期刊名：中国化学快报（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2011_2012】；PubMed;

语种：英文

中文关键词：Mandelonitrile; Nitrilase; (R)-()-Mandelic acid; Screening; Alcaligenes sp. ECU0401

外文关键词：Mandelonitrile; Nitrilase; (R)-()-Mandelic acid; Screening; Alcaligenes sp. ECU0401

摘要：By using acetonitrile as the sole nitrogen source, a microbial strain with high nitrilase activity, named as Alcaligenes sp. ECU0401, was newly isolated from soil, which could enantioselectively transform racemic mandelonitrile into (R)-(?)-mandelic acid, with an enantiomeric excess of >99.9%.
By using acetonitrile as the sole nitrogen source, a microbial strain with high nitrilase activity, named as Alcaligenes sp. ECU0401, was newly isolated from soil, which could enantioselectively transform racemic mandelonitrile into (R)-(?)-mandelic acid, with an enantiomeric excess of >99.9%.