文献类型：期刊文献

英文题名：Apatite-forming ability and mechanical properties of PTMO-modified CaO-SiO2-TiO2 hybrids derived from sol-gel processing

作者：Miyata, Noboru[1]; Fuke, Ken-Ichi[1]; Chen, Qi[2]; Kawashita, Masakazu[1]; Kokubo, Tadashi[1]; Nakamura, Takashi[3]

机构：[1]Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 6068501, Japan;[2]E China Univ Sci & Technol, Dept Inorgan Mat, Shanghai 200237, Peoples R China;[3]Kyoto Univ, Grad Sch Med, Dept Orthopaed Surg, Sakyo Ku, Kyoto 6068507, Japan

年份：2004

卷号：25

期号：1

起止页码：1

外文期刊名：BIOMATERIALS

收录：;EI(收录号：2003457714680);WOS:【SCI-EXPANDED(收录号:WOS:000186674300001)】；

语种：英文

外文关键词：organic-inorganic hybrids; poly(tetramethylene oxide); apatite-forming ability; bioactivity; mechanical properties

摘要：Hydrolysis and polycondensation of triethoxysilane end-capped Poly (tetramethylene oxide) (Si-PTMO), tetraethoxysilane (TEOS), tetraisopropyltitanate (TiPT) and calcium nitrate (Ca(NO3)(2)) gave transparent monolithics of PTMO-modified CaO-SiO2-TiO2 hybrids. The samples with (TiPT)/(TEOS+TiPT) molar ratios from 0 to 0.20 under constant ratio of (Si-PTMO)/ (TEOS + TiPT) of 2/3 in weight were prepared. It was found that the incorporation of TiO2 component into a PTMO-CaO-SiO2 hybrid results in an increase in the apatite-forming ability in a simulated body fluid: the hybrids with (TiPT)/(TEOS + TiPT) of 0.10 and 0.20 in mol formed an apatite on their surfaces within only 0.5 day. It seemed that, within the range of compositions studied, the TiO2 content little affects the overall mechanical properties: Young's modulus were 52-55 MPa, tensile strength, 7-9 MPa, and strain at failure, about 30%. Thus, the organic-in organic hybrids exhibiting both fairly high apatite-forming ability and high capability for deformation were obtained. These hybrid materials may be useful as new kind of bioactive bone-repairing materials. (C) 2003 Elsevier Ltd. All rights reserved.