文献类型：期刊文献

英文题名：Scaling-up molecular logic to meso-systems via self-assembly

作者：Chen, Ze-Qing[1];Daly, Brian[1];Yao, Chao-Yi[2];Crory, Hannah S. N.[1];Xu, Yikai[1,3,4];Ye, Ziwei[1];Gunaratne, H. Q. Nimal[1];Kimura, Ayumi[5];Uchiyama, Seiichi[6];Bell, Steven E. J.[1];Anslyn, Eric V.[1,7];de Silva, A. Prasanna[1]

机构：[1]Queens Univ, Sch Chem & Chem Engn, Belfast BT9 5AG, North Ireland;[2]Cent South Univ, Sch Chem & Chem Engn, Changsha 410006, Hunan, Peoples R China;[3]East China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[4]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[5]Univ Tokyo, Inst Engn Innovat, 2-11-16 Yayoi,Bunkyo Ku, Tokyo 1138656, Japan;[6]Univ Tokyo, Grad Sch Pharmaceut Sci, 7-3-1 Hongo,Bunkyo Ku, Tokyo 1130033, Japan;[7]Univ Texas Austin, Dept Chem, 100 24th St, Norman Hackerman Bldg, Austin, TX 78712 USA

年份：2025

卷号：16

期号：1

外文期刊名：NATURE COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001455352300004)】；

基金：We thank the late Otto S. Wolfbeis and the late Sir J. Fraser Stoddart for support. We thank Queen's University Belfast, Department of Employment and Learning of Northern Ireland, Engineering and Physical Sciences Research Council UK, China Scholarship Council, the Leverhulme Trust (RPG-2019-314) and Ziwei Liu. E.V.A. thanks the Welch Regents Chair for support (F-0046).

语种：英文

摘要：Due to the small size and biocompatibility of molecules, molecular logic-based computation is a gateway to the informational basis of life processes. Logic-based computation operates widely with discrete molecules of up to nanometric sizes. The contribution of molecule-based bulk materials of milli/centimetric size to the field has begun in more recent years. However, artificial molecule-based meso-scale systems which intrinsically perform logic operations are very rare. Here, we show that self-assembled systems consisting of cyclophane octacarboxylates and a cationic surfactant can perform such functions, where a membrane itself behaves as a Reset-Set Flip-Flop which is integrated with 7 more logic elements. Now that molecular logic-based computation operates across a wide range of contiguous size-scales, the way opens for its general use in information processing aspects of biology and synthetic biology.