文献类型：期刊文献

英文题名：Transition-metal-free visible-light photoredox catalysis at room-temperature for decarboxylative fluorination of aliphatic carboxylic acids by organic dyes

作者：Wu, Xinxin[1];Meng, Chunna[1];Yuan, Xiaoqian[1];Jia, Xiaotong[2];Qian, Xuhong[2];Ye, Jinxing[1,3]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Minist Educ, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2015

卷号：51

期号：59

起止页码：11864

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000357804800030)，CCR-EXPANDED(收录号:WOS:000357804800030)】；

基金：This work was partially supported by National Natural Science Foundation of China (21272068), Program for New Century Excellent Talents in University (NCET-13-0800), and the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：We report herein an efficient, general and green method for decarboxylative fluorination of aliphatic carboxylic acids. By using a transition-metal-free, organocatalytic photoredox system, the reaction of various aliphatic carboxylic acids with the Selectfluor reagent afforded the corresponding alkyl fluorides in satisfactory yields under visible light irradiation at room temperature.