文献类型：期刊文献

英文题名：Stirring and electric field assisted microbubble preparation

作者：Zhang, H.B.[1]; Li, J.[1]

机构：[1] School of Mechanical and Power Engineering, East China University of Science and Technology, no.130 Meilong Road, Shanghai 200237, China

年份：2010

卷号：2

期号：1

起止页码：9

外文期刊名：Bubble Science, Engineering and Technology

收录：EI(收录号：20102312989988)

语种：英文

外文关键词：Ultrasonics - Drug delivery - Gene therapy - Electrohydrodynamics - Size distribution

摘要：In this paper, a stirring and electric field assisted microbubble preparation (SEFAMP) method for the preparation of microbubble ultrasound contrast agents is reported. Microbubbles with a narrow size distribution were obtained. The coalescence of microbubbles, which often happens in the stirring method, was eliminated. Addition of polyethylene glycol (PEG) 400 further optimised microbubble size distribution profile. This new method shed a light on realising the microbubble ultrasound agents as drug delivery vehicle and gene therapy for a potential clinical use. ? 2010 W. S. Maney & Son Ltd.