文献类型：专利

英文题名：New benzyl substituted aniline compound used in preparing medicine for preventing or treating diseases associated with farnesyl transferase, including prostate cancer, lung cancer, breast cancer, pancreatic cancer or colon cancer

作者：HUANG J;LI H;XU Y;ZHANG Y;MEI H;ZHAO X;ZHAO Z;YANG L;LUAN G

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN103787902-A

申请日：2014-02-17

公开日：2014-05-14

语种：英文

收录：DERWENT

摘要：NOVELTY - Benzyl substituted aniline compound (I) and its salts are new. USE - Benzyl substituted aniline compound and its salts are used in preparing medicine for preventing or treating diseases associated with farnesyl transferase, including prostate cancer, lung cancer, breast cancer, pancreatic cancer or colon cancer (all claimed). DETAILED DESCRIPTION - Benzyl substituted aniline compound of formula (I) and its salts are new. R1=-COOH, -CONH2, H, -COOR5, -CN, -OH or -NH2COCH3; R5=Me or Et; R2,R3=6-10C aryl, 3-6C cycloalkane, 1-3C alkyl, optionally saturated alkyl; and R4=H, Et or acetyl.