文献类型：期刊文献

英文题名：Direct Oxidation of β-Aryl Substituted Aldehydes to α,β-Unsaturated Aldehydes Promoted by an o-Anisidine-Pd(OAc)₂ Co-catalyst

作者：Liu, Jie[1];Zhu, Jin[1];Jiang, Hualiang[1,3];Wang, Wei[1,2,3];Li, Jian[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA;[3]Chinese Acad Sci, Shanghai Inst Mat Med, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China

年份：2009

卷号：4

期号：11

起止页码：1712

外文期刊名：CHEMISTRY-AN ASIAN JOURNAL

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000271814800010)】；

基金：We gratefully acknowledge the financial support from the National Natural Science Foundation of China (Grant 90813005), the 863 Hi-Tech Program of China (Grant 2006AA020404), the China 111 Project (Grant B07023). and Shanghai Rising-Star Program (A type) of the Shanghai Ministry of Science and Technology (Grant 07A14013).

语种：英文

外文关键词：aldehydes; anisidine; organocatalysis; palladium; Saegusa reaction

摘要：An o-anisidine-Pd(OAc)(2) catalytic system for the direct co-catalytic Saegusa oxidation of beta-aryl substituted aldehydes to alpha,beta-unsaturated aldehydes has been developed. The use of o-anisidine in place of (S)-diphenylprolinol made the process more simply and cost-effective. The process not only features the use of unmodified aldehydes rather than enol silyl ethers, but also gives moderate to good yields (44-72%)