文献类型：期刊文献

英文题名：Effect of surface modification on the peroxidase-like behaviors of carbon dots

作者：Shi, Jing[1];Yin, Tianxiang[1];Shen, Weiguo[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]Lanzhou Univ, Dept Chem, Lanzhou 730000, Gansu, Peoples R China

年份：2019

卷号：178

起止页码：163

外文期刊名：COLLOIDS AND SURFACES B-BIOINTERFACES

收录：;EI(收录号：20191006604007);WOS:【SCI-EXPANDED(收录号:WOS:000471084400020)】；

基金：This work was supported by the National Natural Science Foundation of China (Projects 21773063, 21373085, and 21,303,055).

语种：英文

外文关键词：Nanoenzyme; Peroxidase; Carbon dots

摘要：Carbon dots (CDs) have drawn much attention in recent decades due to their outstanding biocompatibility and environmental friendliness. In this work, the surface modifications of peroxidase-like carbon dots were carried out to show the influence of surface structure on the catalytic activity. Poly(ethyleneimine) and citric acid modified CDs, i.e. PEI-CDs and CA-CDs, were obtained and used in the catalytic oxidation of two different substrates 3,3',5,5'-tetramethylbenzidine (TMB) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). The catalytic activity of CA-CDs for TMB is greater than that of unmodified CDs while the catalytic activity of PEI-CDs for ABTS is greater than that of unmodified CDs. These results may be ascribed to that TMB shows stronger affinity to negatively charged CA-CDs and ABTS shows stronger affinity to positively charged PEI-CDs. These results clearly suggested that the surface charge plays an important role in the catalytic activity of nanoenzyme. Furthermore, the mechanism of peroxidase-like activity of all CDs was investigated and both the generation of hydroxyl radical and enhanced electron transfer were involved in the catalytic process.